A recent study from the University Hospital Southampton has found that all six COVID-19 booster vaccines are safe and effective in producing strong immune responses in individuals who have already received two doses of either the AstraZeneca or Pfizer/BioNTech vaccines. The study, published in The Lancet, analyzed health data from 2,878 individuals who had already been fully vaccinated with either vaccine. The participants, who were between the ages of 51 and 76, received one of the six booster vaccines 10-12 weeks after their second dose.

The study found that all eight booster vaccines led to a significant increase in antibodies against the SARS-CoV-2-Spike-Protein. The researchers noted that while there is currently no established threshold for the concentration of antibodies needed for safe protection, the data from the study suggests that both the same and different vaccines can be used for the third dose. The study also found that all seven vaccines had acceptable side effects, including inflammation at the injection site, muscle pain, and fatigue.

This study comes as concerns grow over the waning effectiveness of COVID-19 vaccines over time. A recent study from Israel found that the protective effects of the Pfizer/BioNTech vaccine decreased significantly after just a few months. The findings from the University Hospital Southampton study provide hope that booster vaccines can help to maintain protection against COVID-19. As the pandemic continues to evolve, it is crucial to continue researching and developing effective strategies to combat the virus.

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