A recent study conducted by scientists at Duke University School of Medicine has found that Pulegone, a monocyclic monoterpene ketone, has been detected in high concentrations in numerous e-cigarette liquids and chewing tobacco. Pulegone was previously used as a flavoring agent in various food products due to its peppermint scent, but was banned by the Food and Drug Administration (FDA) in the United States due to its carcinogenic effects. Despite this ban, the chemical is still legal for use in e-cigarettes and chewing tobacco, as the regulations for these products are less strict than those for food. The study, published in JAMA Internal Medicine, found “concerning levels” of Pulegone in products with mint and menthol flavors, with concentrations exceeding those found in traditional menthol cigarettes by a factor of 86 to 1,608.
While e-cigarettes are considered less harmful than traditional tobacco cigarettes, a study published earlier this year suggests that they still have the potential to cause cancer. Additionally, recent research has shown that even nicotine-free e-cigarette liquids can damage endothelial cells in blood vessels, increasing the risk of heart attacks and strokes. In response to seven deaths linked to e-cigarette use in the United States, President Donald Trump has announced plans for “very strong” regulations for manufacturers. However, it is unclear whether these regulations will address the use of Pulegone in e-cigarette liquids.
The study’s authors have called for stricter regulations on e-cigarette and chewing tobacco products to protect consumers from exposure to Pulegone. While the study only examined products in the United States, it is unclear whether e-cigarette liquids sold in other countries, including Germany, may also contain high levels of the chemical. The German E-Cigarette Trade Association has launched a survey of its members to determine whether Pulegone is being used in e-cigarette liquids sold in Germany. As the debate over the safety of e-cigarettes continues, it is clear that more research is needed to fully understand the potential risks associated with these products.
