Magersucht, also known as anorexia nervosa, has long been thought to be caused by psychological issues. However, recent research suggests that metabolic factors may also play a role in the development of this eating disorder. A study conducted by scientists at King’s College London and the University of North Carolina found that genetic predisposition, as well as stress and social problems, can contribute to the onset of anorexia. The study analyzed the DNA of 17,000 anorexia patients and found eight suspicious DNA sequences on six chromosomes that were not present in healthy individuals. These regions of the genome have also been linked to other biological abnormalities and diseases, such as depression and schizophrenia.
The study also found that the genes responsible for anorexia can affect a range of metabolic characteristics, including blood sugar, fat metabolism, and body measurements. This suggests that metabolic disorders may contribute to the development of anorexia, which was previously thought to be a result of starvation. The researchers argue that anorexia should be re-conceptualized as a “metabolic-psychiatric disorder” to facilitate more effective treatment. Current therapies for anorexia have focused almost exclusively on psychological aspects, but the study’s findings suggest that addressing metabolic factors may also be crucial.
In conclusion, anorexia nervosa is a complex disorder that is caused by a combination of psychological and metabolic factors. The study’s findings suggest that genetic predisposition, stress, and social problems can contribute to the onset of anorexia, and that metabolic disorders may also play a role. By re-conceptualizing anorexia as a “metabolic-psychiatric disorder,” researchers hope to develop more effective treatments that address both psychological and metabolic aspects of the disease.
